• pH-Sensitive Food-Grade Enteroguard Coating
• In Foil Blister Pack
• Natural
• Full Potency
• S-Adenosyl Methionine
• 400 mg (net yield) SAMe from 800 SAMe tosylate disulfate
• Highest Concentration of Active S,S Form
• Entric-Coated Tablets
• Gluten-Free
• Vegan
• Dietary Supplement

Promotes:

• Joint Strength
• Liver Detoxification
• Mood and Brain Function

Jarrow Formulas SAMe 400 provides a full 400 mg SAMe (net yield) from 800 mg of SAMe tosylate disulfate. SAMe 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S,S Form

Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.Jarrow Formulas SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available.

SAMe has been clinically shown to have the following benefits:

Joint Strength

SAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.

Brain Metabolism

SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).

Liver

Full Potency 400 mg SAMe (net yield) is derived from 800 mg of SAMe tosylate disulfate.

For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.

Suggested Use

Other Ingredients: Cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch glycolate and an enteric coating (modified cellulose, magnesium silicate, triethyl citrate and riboflavin).

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

Suitable for vegetarians/vegans.

Warnings:

Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.

Keep out of the reach of children.